Abstract
In the course of development of microspheres preparation techniques, the encapsulation of hydrophilic drugs with high entrapment efficiency has been a problem, as the commonly used technique like single emulsification technique and w/o/w double emulsification technique show low entrapment of the hydrophilic drugs. The problem is overcome by using by using w/o/o double emulsification technique, several modifications have been done in this technique one of most widely and effective technique in w/o/o double emulsification is the solvent diffusion technique. In this brief review comparison of w/o/o double emulsification technique with other methods and details about the w/o/o double emulsification technique and the drugs encapsulated using this technique will be discussed.
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How to cite this article:
Gupta S. K.., Gupta R., Yadav S. K., Kar M., Jain D. K., A review on “Design and development of transdermal drug delivery system ”, Int. J. Res. Dev. Pharm. L. Sci., 2013, 2(6), pp. 667-673.
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