Abstract
During the last decade, there are new developments in site-specific formulations for targeting drugs to the colon. Colon has proved to be a site for the absorption of poorly soluble drugs. Micro carriers as colon drug delivery System has gained importance for the delivery of the drug in the colon because of their increase biocompatibility, controlled release of drug and higher stability. This review is discussed in brief about the introduction to the colon, Micro Carrier as a colon drug delivery system. Microcarrier may include Microspheres, Nanoparticles, and Granules, etc.
References
Anil K. Philip. Colon Targeted Drug Delivery Systems: A Review on Primary and Novel Approaches. OMJ. 2012; 70-78.
Behera B.C, Sahoo S.K, Dhal S, Barik B.B, Gupta B.K; A research article on Charcterization of Glipizide-loaded polymethacrylate Microsphere prepared by an Emulsion Solvent Evaporation Method. Tropical Journal of Pharmaceutical Research. 2008 7(1) pp 879-885.
Behin S.R, Punitha I.S, Prabhakaran P, Kundaria J; A Research article on Design and Evaluation of coated microsphere of antiprotozoal drug for colon specific delivery. American journal of pharmatech Research. 2013 3(4).
Devrim B. and Canefe K*; A research article on Prepration and Evaluation of Modified Release Ibuprofen Microspheres with Acrylic Polymers by Quasiemulsion Solvent diffusion method. Acta Poloniae Pharmaceutica. Drug Research, Vol. 63 No. 6 pp. 521- 534, 2006
Deveswaran R*, Manavalan R,Madhavan V,Bharath S; A Research article on Formulation and evauation of Albumin microsphere containing acelofenac. Tropical Journal of Pharmaceutical Research. Volume 4, Issue 1 2008.
EuropeanPharmacopoeia 5th Edition 2005.
Graud N, Badhana S, Graud A; A research article on Colon specific drug delivery of mesealamine using eudragit S100 Coated Chitosan Microsphere. International Current Pharmaceutical Journal. 2003 2(3) 42-49.
Gulhati CM: Monthly index of medical specialties 2010; 30(2): 22-24.
Gurpreet Kaur*, Maninderjit kaur, Harpreet kaur, Saurav Sharma: Colon Specific Drug Delivery System:A Review on different approaches to treat colon disease. International journal of Pharmaceutical Research and development. 0974 – 9446
Hardenia S.S*, JainA., Patel R, Kaushal A; A reserach article on Formulation and Evaluation of Mucoadhesive Microspheres of Ciprofloxacin. Journal of Advanced Pharmacy Education & Research 1(4): 214-224 (2011) ISSN 2249-3379
Koteshwara K.B. Primary and novel approaches for colon targeted drug delivery – A review. Int. Journal of Research in Ayurvedic & Pharmacy.2011; 2 (1): 60-65.
Mishra J, Kalia A: A Research article on “Indomethacin Granules for Colon specific drug delivery system”. International journal of Pharmaceutical and Chemical Science. Vol. 3 (1) Jan-Mar 2014.
Mohapatra D.K, Sawagatik M: A research Article on “5-Fluoro Uracil for colon specific drug delivery of a Poly (CarboxyMethyl Cellulose-co-Acryl Amide)/MBA Nano Sized Hydrogel”. International Journal of Pharmaceutial and Chemical Science. Vol. 1 (1) Jan – Mar 2012
Pachuau L*,Sarkar S. and Mazumder B ;A Research Article on Formulation and evaluation of matrix microspheres for simultaneous delivery of salbutamol sulphate and theophylline. Tropical Journal of Pharmaceutical Research, June 2008; 7 (2): 995-1002
Choudhury P.K*, Murthy P.M,Tripathy N.K. Aresearch article on Formulation And development of Acrycoat 100 Coated Calcium alginate microsphere for colon drug delivery. International jounal of pharmaceutical research. 2012.
Choudhury P.K*, Murthy P.M, Tripathy N.K, Patra B.S. A research article on Formulation And development of enteric coated matrix tablets for colon drug delivery of ornidazole. Asian journal of pharmaceutica and clinical research. 2012 3 (5)
Patel B, Modi V, Patel K, Patel M ; A Research article “Prepration and Evaluation of Ethyl Cellulose Microsphere by Emulsification Solvent Evaporation Method.International Journal for Research in Management and Pharmacy. Vol.1, Issue: 1 December: 2012
Reddy R V* and Niranjan M.B .A research article on Formulation and in vitro evaluation ornidazole film coated tablets for colon drug delivery.International journal of pharmaceutical research in nano Sciences. 2(6) 2013
Ratnaparkhi Mukesh P.,*Somvanshi Fattesingh U., Mane Chaitali V., Pawar Sham A., Chaudhari Shilpa P. A Research Article on Formulaion And development of enteric coated tablets of ornidazole for colon Drug delivery. Journal of drug and discovery therapeutics. 2013 1(15)
Rajana M., V. Raja, Abdullah A. Al-Arfaj, A.M. Murugan: A Research article on “Hyaluronidase enzyme core-5-fluorouracil-loaded chitosan-PEG-gelatin polymer nanocomposites as targeted andcontrolled drug delivery vehicles”.International Journal of Pharmaceutics. (2013) 514– 522
Rout P.K, Ghosh A, Nayak A.K, Nayak B;A Research article on Preparation and Evaluation of losartan Containing Microsphere. International Journal of Pharmacy and Pharmaceutical Sciences. Vol 1, Issue 1 July- Sep 2009.
Shah N, Patel B, Thakkar Y.T, Bharadia P.D. A review on polymeric microsphere as new noveldrug carrier; Int.
J. of Universal Pharm. & Life Sci., 2(3): 2012; 256-271
Sreelatha D, Brahma C.K. A Review on primary and novel approaches of colon targeted drug delivery system. Journal of Global Trends in Pharmaceutical Sciences. 2012; 4(3): 1174-118
Sriram N. and Bindu R.H; A research article on formulation and evaluation of glimipride Microsphere. International Journal of Phamaceutical Development & Technology. 3 (1), 2013, 7-12.
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