Abstract
Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. Niosomes are formations of vesicles by hydrating mixture of cholesterol and nonionic surfactants. Different novel approaches used for delivering these drugs include liposomes,microspheres, nanotechnology, micro emulsions, antibody loaded drug delivery, magnetic microcapsules, implantable pumps and niosomes. Niosomes and liposomes are equiactive in drug delivery potential and both increase drug efficacy as compared with that of free drug. Niosomes are now widely studied as an alternative to liposomes . They improve the therapeutic performance of the drug molecules by delayed clearance from the circulation, protecting the drug from biological environment and restricting effects to target cells. The application of niosomal technology is widely used to treat a number of diseases.
References
REFERENCES:
Madhav et al. ISSN: 2231□2781 IJRPC 2011, 1(3),498- 499.
Allen TM: Liposomal drug formulations: Rationale for development and what we can expect for the future. Drugs,1998, (56), 747-756
Handjani-vila RM: Dispersion of lamellar phases of nonionic lipids in cosmetic products. Int J Cosmetic Sci, 1979; 1: 303.
Mehta A: Niosomes. www.pharmainfo.net. 2009.
www.ijrpbsonline.comApr – Jun2012Vol. 3 (2),722
Buckton G, Harwood. Interfacial phenomena in Drug Delivery and Targeting Academic Publishers, Switzerland.1995; 154-155.
Int. J. Pharm. Sci. Rev. Res., n□ 22, ISSN 0976 – 044X15,2012; (1), 113 -114
Gadhiya P, Shukla S, Modi D, Bharadia P, A Review- Niosomes in Targeted Drug Delivery, International Journal for Pharmaceutical Research Scholars, 2012,2, 61.
Ashish Kumar Verma et al / Indian Journal of Novel Drug Delivery 3(4), Oct-Dec, 2011;3(4): 238-239.
Rogerson A., Cummings J., Willmott N. and Florence A.T. The distribution of doxorubicin in mice following administration in niosomes. J Pharm Pharmacol. 1988; 40(5): 337–342
Baillie A.J., Coombs G.H. and Dolan T.F. Non-ionic surfactant vesicles, niosomes, as delivery system for the anti-leishmania drug, sodium stribogluconate J.Pharm.Pharmacol. 1986; 38: 502-505.
Khandare JN, Madhavi G and Tamhankar BM. Niosomes Novel Drug Delivery System. The Eastern Pharmacist. 1994;37:61-64.
Chauhan S, Luorence MJ, The preparation of polyoxyethylene containing non-ionic surfactant vesicles. J Pharm Pharmacol, 1989, (41), 6.
Raja Naresh R.A., Anti-inflammatory activity of Niosome encapsulated diclofenac sodium with Tween -85 in Arthitic rats. Ind.J.Pharmacol. 1994;26: 46-48.
Malhotra M, Jain NK: Niosomes as Drug Carriers. Indian Drugs, 1994, (31), 81-86.
Gregoriadis G: Targeting of drugs: implications in medicine. Lancet, 1981, (2), 241-246.
Weissman G et al: General method for the introduction of enzymes, by means of immunoglobulincoated liposomes.
Yoshida H et al: Niosomes for oral de-livery of peptide drugs. J Control Rel, 1992, (21), 145–153.
Brewer JM and Alexander JA: The adjuvant activity of nonionic surfactant vesicles (niosomes) on the BALB/c humoral response to bovine serum albumin. Immunology, 1992, (75), 570-575.
Moser P et al: Niosomes d’hémoglobine, Preparation, proprietes physicochimiques oxyphoriques, stabilite. Pharma Acta Helv, 1989, (64), 192-202
Jayaraman SC, Ramachandran C, Weiner N: Topical delivery of erythromycin from various formulations: An in vivo hairless mouse study. J Pharm Sci, 1996, (85), 1082-1084.
Luciani A: Glucose Receptor MR Imaging of Tumors: Study in Mice with PEGylated Paramagnetic Niosomes. J Radiology, 2004, (2), 135.
Aggarwal D et al: Development of topical niosomal preparation of acetazolamide: preparation and evaluation. J Pharm Pharmacol, (2004), 56: 1509.
Chauhan S. and Luorence M.J. The preparation of polyoxyethylene containing non-ionic surfactant. vesicles. J. Pharm. Pharmacol. 1989; 41: 6p.
Suzuki K. and Sokan K. The Application of Liposomes to Cosmetics. Cosmetic and Toiletries. 1990; 105: 65-78.
Breimer DD and Speiser R. Topics in Pharmaceutical Sciences. Elsevier Science Publishers, New York, USA. 1985;291.
Azmin MN, Florence AT, Handjani VRM, Stuart JFB, Vanlerberghe G, and Whittaker JS. The Effect of Non- Ionic Surfactant Vesicle (niosome) Entrapment on the Absorption and Distribution of Methotrexate in Mice. J Pharm Pharmacol. 1985;37:237–242
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Copyright (c) 2020 Array