Peer Review, UGC Care
EFFECT OF EXPERIMENTAL INDUCED HYPOCALCEMIA ON PHYSICAL PARAMETERS AND CALCIUM LEVELS IN AWASSI SHEEP
View PDF

Keywords

sheep, hypocalcaemia, clinical signs.

How to Cite

Wassan, A.G., & Alawy, M. H. (2015). EFFECT OF EXPERIMENTAL INDUCED HYPOCALCEMIA ON PHYSICAL PARAMETERS AND CALCIUM LEVELS IN AWASSI SHEEP. International Journal of Research and Development in Pharmacy & Life Sciences, 4(6), 1808-1812. Retrieved from https://ijrdpl.com/index.php/ijrdpl/article/view/420

Abstract

This study was induced to record the clinical signs and calcium levels in cases of induce calcium deficiency in Awassi ewes and to investigate the changes of these parameters after treatment. A study included sixty one Awassi ewes, ages ranged between 2-2.5 years and body weigh between 35-45 kg, divided to fourgroups: group one included ten ewes induce in hypocalcaemia and then treated, group two included ten ewes with clinical case: suffering from hypocalcaemia within area of Ab-Grab, group three included thirty ewes suffering from hypocalcaemia in Hours racing of Al-Amara, and group four included ten ewes considered as control group. Group one and four have a preparation period for one month. During this period they fed the same dietary material consist of concentrate and green forage, and injected Ivermectin subcutaneously and multivitamin intramuscularly and gave mineral block and drainage by Vimazole orally, then examined to insure no present of nutritional diseases, then induce hypocalcaemia in group one by injection of Na2EDTA in jugular vein, then take blood samples by different time besides recording the clinical signs. After clinical signs appear group one treated by using one of calcium compound which is Ca Gluconate monohydrate in three doses for two weeks. At the end period of treatment, blood samples was taken for this group.

Results showed a significant difference (P<0.05) in temperature, pulse and respiration in all groups compared with control group, as well as, the measurement of calcium levels in serum.

View PDF

References

Armstron, C.M. and Cota, G.(1999). Calcium block of Na+ channels and its effect on closing rate". Proceedings of the National Academy of Sciences of the United States of America. 96, (7): 4154– 4157. Bibcode: 1999PNAS. 96.4154A

Ferdinan, M. (1983). Polyamino carboxylic acids to

I. G. Farbenindustrie, DE 718 981, 1935; US 2 130 505, 1938.

Fenwick, D.C and Danial, R.C.W (1992). Blood pathophysiological changes in sheep following a prolonged (18-hour) period of hypocalcaemia induce by Na2EDTA solution . British Veterinary J., 148(5):425-434.

Ignatavicius, D. and Workman, ML., eds (2010). Medical-surgical Nursing: Patient-centered Collaborative Care. 6th ed. St. Louis, MO: Elsevier Saunders.

Jensen, R. and Swift, B. L. (1982(: Disease of Sheep. 2nd ed. Lea & Febiger, Philadelphia., 19-28.

Jorgensen, Rj; Nyengaard, NR; Danial, RCW; Mellau, LSB; Enemark, JMD.(1999). Induced hypocalcemia by Na2EDTA infusion. A Review .J. Vet. Med. 46:389-407.

Kaneko, JJ. (1989). Clinical biochemistry of domestic animals, ed 4, New York, Academic Press.

Kott, R. (2005). Diseases and Disorders Commonly Seen in Ewes Just Prior to or Shortly After Lambing Extension Sheep Specialist, Montana State University.

Merck and Co (2008) .The Merck Veterinary Manual, a subsidiary of Merck and Co., Inc., Whitehouse Station, N.J., U.S.A.

Persson, j and luthman, j. (1975). Futher studies on theophylline-induced hypocalcaemia in sheep. Act veterinaria Scandinavica; v16(1):39-50.

Pickard, D.W. (1987) : Hypocalcemia in ewes. Vet. Record, 1987, 122 (4), 92.

Radostits, O.M.; Gay, CC.; Blood, D.C. and Hinchliff,

k.w. (2008). Veterinary medicine. A textbook of the diseases of cattle, sheep, pigs, goats and horses, 10th ed .w.B. saunders company Ltd. London . New York. phliladelphia, san Francisco. Sydney.

Robinson, W.F (1988). Clinicopathological principles for veterinary medicine. Cambridge University Press, New York, New Rochel , 389-398.

Schlumbohm, C.; Harmeyer, J. (2003). Hypocalcemia reduces endogenous glucose production in hyperketonemic sheep. J. Dairy Sci.; 86(6): 1953-1962.

Smith,B.p.(2009). Large animal internal medicine .4th ed .Mosby Elsevier. St.louis,Missouri.

Sweeney, H. J.and Cuddeford, D. (1987).An outbreak of hypocalcaemia in ewes associated with dietary mismanagement. Vet. Record 120, ( 5):114.

Takagi, H. and Block, E.(1991). Effects of various dietary cation-Anion balances on response to Experimentally induced hypocalcemia in sheep .J. Dairy sci. 74:4215-4224.

Wilson, G-F.(2001). Stimulation of Ca absorption and reduction in susceptibility to fasting-induced hypocalcaemia in pregnant ewes fed vegetable oil.New Zealand veterinary Journal; v 49(3):115- 118.

Woldemeskel, M.; Eneyew, M. and Kassa, T. (2000). Study on ovine hypocalcemia in ewes in central Ethiopia. Revue. Med.Vet., 151,4,345-350.

Young, DS.(1990). Effects of drugs on clinical laboratory tests. AACC press, Washington, D.C.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

Copyright (c) 2020 Array

Downloads

Download data is not yet available.