Abstract
Floating drug delivery systems (FDDS) was to organize the recently focus on the principalmechanism of floatation to achieve gastric retention time. The recent developments of FDDS including thephysiological and formulation variables affecting gastric retention, approaches to design floating systems, and their classification and formulation aspects are covered in detail. Gastric emptying ofdosage forms is an extremely variable process and ability to prolong and control the gastric emptying time is a valuable asset for dosage forms, which reside in the stomach for a longer period of time than conventional dosage forms. Gastroretentive systems can remain in the gastric region for several hours for significantly prolong residence time of drugs by which improves bioavailability, reduces drug waste, and improves solubility for drugs that are less soluble in a high pH environment.. The present review addresses briefly about the floating drug delivery systems.
References
REFERENCES
Vyas SP, Roop KK. Floating DrugDelivery Concepts and Advances, First Edition, New Delhi. 2002; 196-217.
Jain NK. Progress in Controlled and Novel Drug Delivery Systems. First Ed. CBSS.Gopalakrishnan et al,Journal of Pharmaceutical Science and Technology. Publishers and Distributors, New Delhi,Bangalore. 2004; 3(2): 84-85. Lovenish Bhardwaj, Pramod Kumar Sharma; A short review on gastro retentive formulations for stomach specific drug delivery: special emphasis on floating in situ gel systems; African journal of basic and applied sciences 3 (2011) 300-312.
Agyilirah GA, Green M and Ducret R. Evaluation of the gastric retention properties of a cross linked polymer coated tablet versus those of a non‐disintegrating tablets. Int J Pharm. 1991;75:241‐247.
Hoffman F, Pressman JH and Code CF. Controlled entry of orally administered drugs, physiological considerations. Drug Dev Ind Pharm. 1983;9:1077‐1085.
Streubel A, Siepmann J and Bodmeier R. Gastroretentive drug delivery system. Expert Opin Drug Delivery. 2006;3(2):217- 33.
Desai S. A Novel Floating Controlled Release Drug Delivery System Based on a Dried Gel Matrix Network [master’s thesis]. [thesis]. Jamaica, NY: St John’s University; 1984.
Hoffmann A. Pharmacodynamic aspects of sustained release preparations. Adv. Drug. Deliv. Rev 1998; 33 : 185-199.
Stanley SD, Lisbeth I. Drug delivery systems for challenging molecules. Int. J. Pharm. 1998; 176 : 1-
Hirtz, The GIT absorption of drug in man: a review of current concepts and method of investigation, British Journal of Clinical Pharmacology. 1985, 19, 77-83.
S. Gopalakrishnan and A. Chenthilnathan; Floating Drug Delivery Systems: A Review, Journal of Pharmaceutical Science and Technology 3 (2011) 548- 554.
Sharma N, Agarwal D, Gupta M and Khinchi M. A comprehensive Review on Floating Drug Delivery System. Int J Res Pharm Biomed Sci. 2011;2:428-441.
Klausner EA, Sara E, Lavy E, Friedman M, Hoffman A. Novel levodopa gastro-retentive dosage form: in-vivo evaluation in dogs. J. Control. Release, 2003; 88:117- 126.
Kale RD, Tayade PT. A multiple unit floating drug delivery system of Piroxicam using Eudragit polymer. Indian J PharmScie 2007; 69(1): 120-123.
Narang N. An updated review on: floating drug delivery system (FDDS). International Journal of Applied Pharmaceutics. 2011; 3, 01-07.
Rathod H, Patel V and Modasia M. Floating drug delivery system: Innovative Approach of Gastroretention. Int J Pharm Sciences Review and Research. 2010;4(3):183-191.
Patel R. Recent development in floating drug delivery system for gastric retention of drugs: an overview. 2007;http://www.swatijaininst.com/etechno/feb200 7/roma.rtf.
Mayavanshi AV, Gajjar SS. Floating drug delivery systems to increase gastric retention of drugs: A Review. J Pharm Tech 2008; 1(14): 345‐348.
Fell J T, Whitehead L, Collet H, Prolonged gastric trtention using floating dosage forms, Pharm Technol. 2000; 24(3):82-90.
Moursy NM, Afifi NH, Ghorab DM, El-Saharty Y. Formulation and evaluation of sustained release floating capsules of Nicardipine hydrochloride. Pharmazie. 2003; 58:38-43.
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