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ANALGESIC AND CNS DEPRESSANT ACTIVITY OF METHANOLIC EXTRACTS OF CISSUS VITEGENIA AND CISSUS PALLIDA
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Keywords

Cissus pallida, Cissus vitegenia, CNS depressant activity, analgesic, methanolic extract.

How to Cite

Parimala, S. ., Kumar, V. H. ., Kumar, , S. M. S., Suthakaran, R. ., & Selvan, A. T. . (2013). ANALGESIC AND CNS DEPRESSANT ACTIVITY OF METHANOLIC EXTRACTS OF CISSUS VITEGENIA AND CISSUS PALLIDA. International Journal of Research and Development in Pharmacy & Life Sciences, 2(2), 330-332. Retrieved from https://ijrdpl.com/index.php/ijrdpl/article/view/281

Abstract

The main aim of the present study was to evaluate analgesic and CNS depressant activity of methanolic extracts of stem and roots of Cissus pallida and aerial parts of Cissus vitegenia in experimental animals. The analgesic activity was evaluated by Eddy’s hot plate method and CNS depressant activity was evaluated by using digital actophotometer. The study was carried out by using two different doses (200 and 400mg/kg body weight) of both the extracts. The preliminary pharmacological screening showed that both the extracts showed moderate analgesic activity and significant CNS depressant activity.

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References

MC Cafferey M, Nursing management of the patient with pain, Lippincott, Philidelphia, 1972.

Turk DC, Dworkin RH, What should be the core outcome in chronic pain clinical trials? Arthritis research and therapy.2004; 6(4);151-54.

Lynn B, Holdee AV, Wintoww Cutaneous nociceptors in the neurobiology of pain, Manchester, UK, Manchester university of Press 1984;pp106.

Bernston GG, Cacioppo JT, Shah JY, Gardener WL. The neuro evolutionary of motivation in handbook of motivation science, Newyork, Guildford press, 2008, pp191.

Ban TA, et al, Therapeutic monograph on anxiolytic, Sedative drugs CMAJ.1981-124; 1439-46.

Hwa YC, Jung HP, Jin TH, Hwan SY, Sukjil S, Bang YH et al, Anxiolytic like effects of Gensinosides on the elevated plus maze model.BW/Pharm.Bull.2005;28(9);1621-25.

Thakur Vd, Mungi,SA, Neuropharmacological profile of Eclipta alba(Linn), Hassk, J of Ethanopharmacology; 2005; 85; 514-19.

Cissus Germ plasm resources informative network. United States dept of agriculture;2006-04-03.Trtrieved 2010-07-07

Madhava chetty K, Siraji K,T ulasi rao, Flowering plants of chittor district. Andhra Pradesh, India.

Ghosh MN, Fundamentals of Experimental Pharmacology 2nd edition Calcutta, Scientific book agency, 1984, p144-58.

Turner RA, Screening methods in pharmacology, Academic press, Newyork, 1 965, 158.

Eddy s NB, Leimbach DJ, Synthetic analgesics 2 dithienyl butenyl and dithienyl butylamines. Retrieved by Turner RA, Screening methods in Pharmacology.1 ed, Newyork London, Academic press, 1965, 105-109, J of Pharmacol Therapeutics,1953,107(3)385-93.

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