ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS

Authors

  • Anupriya A Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
  • Priyanka N Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
  • Vallab Ganesh Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
  • Uma A Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.

Keywords:

Anti-Hepatitis B surface antigen; Health care workers; Hepatitis B virus vaccine.

Abstract

ABSTRACT

Objectives: HBV vaccination leads to both humoral and cellular immune response and can be evaluated using HBs- specific antibodies.

Methods: Cross-sectional study was carried out at tertiary care hospital. A total 120 HBV vaccine compliant HCW were evaluated for quantitative anti-HBs by enzyme immune assay.

Results: 110 (91.7%) subjects had protective levels of anti-HBs. Higher age at vaccination was an important risk factor in low vaccine response. Doctors had higher levels of anti-HBs titres when compared to laboratory technicians and staff nurse.

Conclusion: We recommend that all HCWs should undergo ‘initial anti-HBs’ assay within one to three months (less than six months) of last dose of primary vaccination .HCW having initial anti-HBs titers of less than 10 mIU/ml should be investigated for HBV infection and if negative, they should be offer second HBV vaccination series.

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Published

2016-09-15

How to Cite

Anupriya A, Priyanka N, Ganesh, V. ., & Uma A. (2016). ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS. International Journal of Research and Development in Pharmacy & Life Sciences, 5(5), 2307-2310. Retrieved from https://ijrdpl.com/index.php/ijrdpl/article/view/255

Issue

Vol. 5 No. 5 (2016): Volume 5 Issue 5, August - September (2016)

Section

Research
Creative Commons License

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.