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ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS
Vol. 5 No. 5 (2016), Research
Vol. 5 No. 5 (2016)

ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS

Research
Published 2016-09-15
Anupriya A
Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
Priyanka N
Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
Vallab Ganesh
Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
Uma A
Department of Microbiology, Chennai Medical College Hospital and Research Centre (SRM Group), Tiruchirapalli, India.
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Keywords

Anti-Hepatitis B surface antigen; Health care workers; Hepatitis B virus vaccine.

How to Cite

Anupriya A, Priyanka N, Ganesh, V. ., & Uma A. (2016). ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS. International Journal of Research and Development in Pharmacy & Life Sciences, 5(5), 2307-2310. Retrieved from https://ijrdpl.com/index.php/ijrdpl/article/view/255
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Abstract

ABSTRACT

Objectives: HBV vaccination leads to both humoral and cellular immune response and can be evaluated using HBs- specific antibodies.

Methods: Cross-sectional study was carried out at tertiary care hospital. A total 120 HBV vaccine compliant HCW were evaluated for quantitative anti-HBs by enzyme immune assay.

Results: 110 (91.7%) subjects had protective levels of anti-HBs. Higher age at vaccination was an important risk factor in low vaccine response. Doctors had higher levels of anti-HBs titres when compared to laboratory technicians and staff nurse.

Conclusion: We recommend that all HCWs should undergo ‘initial anti-HBs’ assay within one to three months (less than six months) of last dose of primary vaccination .HCW having initial anti-HBs titers of less than 10 mIU/ml should be investigated for HBV infection and if negative, they should be offer second HBV vaccination series.

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