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ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS
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Keywords

Anti-Hepatitis B surface antigen; Health care workers; Hepatitis B virus vaccine.

How to Cite

Anupriya A, Priyanka N, Ganesh, V. ., & Uma A. (2016). ANTIBODY TO HEPATITIS B SURFACE ANTIGEN IN VACCINATED HEALTH CARE WORKERS. International Journal of Research and Development in Pharmacy & Life Sciences, 5(5), 2307-2310. Retrieved from https://ijrdpl.com/index.php/ijrdpl/article/view/255

Abstract

ABSTRACT

Objectives: HBV vaccination leads to both humoral and cellular immune response and can be evaluated using HBs- specific antibodies.

Methods: Cross-sectional study was carried out at tertiary care hospital. A total 120 HBV vaccine compliant HCW were evaluated for quantitative anti-HBs by enzyme immune assay.

Results: 110 (91.7%) subjects had protective levels of anti-HBs. Higher age at vaccination was an important risk factor in low vaccine response. Doctors had higher levels of anti-HBs titres when compared to laboratory technicians and staff nurse.

Conclusion: We recommend that all HCWs should undergo ‘initial anti-HBs’ assay within one to three months (less than six months) of last dose of primary vaccination .HCW having initial anti-HBs titers of less than 10 mIU/ml should be investigated for HBV infection and if negative, they should be offer second HBV vaccination series.

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