Abstract
The effect of alcoholic extract of Nigella Sativa was investigated in rats to evaluate the anti-ulcer activity by using two models, i.e. Pyloric ligation and aspirin Induced gastric ulcer. The parameters taken to assess anti ulcer activity were volume of gastric secretion, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, free acidity, total acidity and ulcer index with respect to control.
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