Abstract
Ritonavir is an anti-retroviral agent used in the treatment of AIDS having lowest water solubility of about 0.01mg/ml, indicates class IV drug biopharmaceutical classification systems, make an objective to study the solubility and dissolution by solid dispersion technique. Ritonavir solid dispersions are prepared using maltodextrin and poloxamer by solvent evaporation and kneading method at 1:1 and 1:3 drug: carrier and were evaluated for drug content, solubility, saturation solubility, FTIR, XRD, DSC and in-vitro dissolution.
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How to cite this article
Swathi P. and Anand YK. Formulation and Evaluation of Ritonavir Solid Dispersions. Int. J. Res. Dev. Pharm. L. Sci. 2017; 6(2): 2522-2529.doi: 10.13040/IJRDPL.2278-0238.6(2).2522-2529.
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