Morphological Spectrum of Glial Tumors in J.A. Group of Hospitals, G.R. Medical College, Gwalior

Authors

  • Bhavna Karnwal Department of Pathology, G.R. Medical College, Gwalior, India
  • Raj Laxmi Sharma Department of Pathology, G.R. Medical College, Gwalior, India
  • Reena Jain Department of Pathology, G.R. Medical College, Gwalior, India
  • Bharat Jain Department of Pathology, G.R. Medical College, Gwalior, India

DOI:

https://doi.org/10.21276/IJRDPL.2278-0238.2018.7(3).3011-3014

Keywords:

Brain tumors, glial tumors, haematoxylin, Astrocytomas

Abstract

Background: Brain tumors represent a unique, heterogenous population of neoplasms that include both benign and malignant tumors. International data depict that tumors of central nervous system account for 1- 2% of all neoplasm. This study was designed to assess the histopathologic spectrum of glial tumors in Indian population which will guide the clinicians to establish measures for an improved diagnosis and management protocols including the use of targeted chemotherapy for specific subtypes.

Method: 117 cases of glial tumors who underwent neurosurgery for space occupying lesions of the brain were enrolled. After gross examination routine histological sections were made using haematoxylin and eosin stains. The diagnosis and grading were done according to WHO classification of CNS tumors.

Result: Most common age of presentation of glial tumours was 31 -45 yrs age group (41%) followed by 46 -60 yrs (30.7%). Males were affected more commonly with sex ratio of 1.9:1. Astrocytomas were the most common glial tumours in our population with grade II astrocytoma being most common followed by grade III tumours.

Conclusion: Among 117 cases which were analysed; 87 were Astrocytomas, 11 were Ependymoma, 12 were glioblastoma multiforme and 7 were oligodendroglioma. The knowledge of histopathologic spectrum of glial tumors in our population will guide the clinicians to establish measures for an improved diagnosis and management protocols.

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How to cite this article:

Karnwal B, Sharma RL, Jain R and Jain B. Morphological Spectrum of Glial Tumors in J.A. Group of Hospitals, G.R. Medical College, Gwalior. Int. J. Res. Dev. Pharm. L. Sci. 2018; 7(3): 3011-3014. doi: 10.13040/IJRDPL.2278-0238.7(3).3011-3014

This Journal is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

Published

2018-06-15

How to Cite

Karnwal, B. ., Sharma, R. L. ., Jain, R. ., & Jain, B. . (2018). Morphological Spectrum of Glial Tumors in J.A. Group of Hospitals, G.R. Medical College, Gwalior. International Journal of Research and Development in Pharmacy & Life Sciences, 7(3), 3011 - 3014. https://doi.org/10.21276/IJRDPL.2278-0238.2018.7(3).3011-3014