Clinico-microbiological profile of Chronic Suppurative Otitis media in a Tertiary Care Hospital


  • Diljot Sandhu Department of Microbiology, Dayanand Medical College & Hospital, Ludhiana, India
  • Veenu Gupta Department of Microbiology, Dayanand Medical College & Hospital, Ludhiana, India
  • Deepinder K. Chhina Department of Microbiology, Dayanand Medical College & Hospital, Ludhiana, India
  • Manish Munjal Department of ENT, Dayanand Medical College & Hospital, Ludhiana, India



Chronic suppurative otitis media, Pseudomonas aeruginosa, Staphylococcus aureus, Ciprofloxacin


Background: Chronic suppurative otitis media (CSOM) is a notorious ear infection and a major health problem in developing countries causing serious local damage and threatening complications. Early and effective treatment based on the knowledge of causative microorganisms and their antimicrobial sensitivity can ensure prompt clinical recovery and possible complications can thus be avoided.

Objectives: To study the clinico-microbiological profile of CSOM.

Materials and Methods: Clinically diagnosed cases of CSOM were enrolled in the study and the ear discharge was obtained using two separate pre?sterilized swabs. They were processed for aerobic & anaerobic culture and sensitivity. Drug susceptibility testing was done using Kirby Bauer disc diffusion method.

Results: Total of 72 patients clinically diagnosed with CSOM were enrolled in our study. Majority of the patients who had ear discharge were in the age group of 41-60 years. 29 cases were of Safe/ tubotympanic type & 43 cases of Unsafe/ atticoantral type of CSOM. Out of 60 positive samples, 54 (90%) had monomicrobial, while 6 (10 %) had polymicrobial growth. Amongst the 66 aerobic isolates, most common causative organisms isolated were Pseudomonas aeruginosa (59%) and Staphylococcus aureus (24.2%). Antimicrobial profile of Gram negative isolates revealed maximum sensitivity to piperacillin, piperacillin-tazobactum, imipenam and ciprofloxacin. All Gram-positive isolates were sensitive to vancomycin, teicoplanin & linezolid.

Conclusion: Continuous and periodic evaluation of microbiological pattern and antibiotic sensitivity of isolates is necessary to decrease the potential risk of complications by early institution of appropriate treatment.


Download data is not yet available.


Acuin J. (2004) Global burden of disease due to chronic suppurative otitis media: Disease, deafness, deaths and DALYs Chronic Suppurative Otitis Media-Burden of Illness and Management Options. Geneva: World Health Organization. p. 9-23.

Woodfield G, Dugdale A. (2008) Evidence behind the WHO guidelines: hospital care for children: What is the most effective antibiotic regime for chronic suppurative otitis media in children. J Trop Pediatr; 54(3):151-6.

Report of WHO/CIBA Foundation workshop. (1996) Prevention of hearing impairment from chronic otitis media. World Health Organization.

Poorey V K, Iyer A. Study of bacterial flora in CSOM and its clinical significance. Indian J of Otolaryngol and Head and Neck Surg 2002; 54: 91-5.

Rout MR, Mohanty D, Vijaylaxmi Y, Kamalesh B, Chakradhar M. (2012) Prevalence of cholesteatoma in chronic suppurative otitis media with central perforation. Indian J Otol; 18:7-10.

Berman S. (1995) Otitis media in developing countries. Pediatrics; 96:126-31.

Wiwanitkit S, Wiwanitkit V. (2012) Pyogenic brain abscess in Thailand. N Am J Med Sci; 4:245-8.

Muftah S, Mackenzie I, Faragher B , Brabin B. (2015) Prevalence of Chronic Suppurative Otitis Media and Associated Hearing Impairment Among School-aged Children in Yemen. Oman Med J;30(5):358-65.

Hassan O, Adeyemi. (2007) A study of bacterial isolates in cases of otitis media in patients attending Oautch, Ile?Ife. Afr J Exp Microbiol; 8:130-6.

Mackie TJ, McCartney JE. (2014) Practical Medical Microbiology. 14th ed. Elsevier.

CLSI. (2015) Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fifth Informational Supplement. CLSI document M100-S25. Wayne, PA: Clinical and Laboratory Standards Institute.

Nwabuisi C, Ologe FE. (2002) Pathogenic agents of Chronic Suppurative Otitis Media in Ilorin, Nigeria. East African Medical Journal; 79(4):202-5.

Mansoor T., Musani M., Khalid G., Kamal M. (2009) Pseudomonas aeruginosa in Chronic Suppurative Otitis Media: Sensitivity Spectrum against various Antibiotics in Karachi. J Ayub Med Coll Abbottabad;21(2):120-3.

Raakhee T., Unguturu SR. (2014) Bacteriological study of discharging ear in patients attending a tertiary care hospital Int J Res Med Sci.;2(2):602-60.

Agrawal A, Kumar D, Goyal A, Goyal S, Singh N, Khandelwal G. (2013) Microbiological profile and their antimicrobial sensitivity pattern in patients of otitis media with ear discharge. Indian J Otol; 19(1).

Gul HC, Kurnaz A, Turhan V, Oncül O, Pahsa A. (2006) Microorganisms isolated from middle ear cultures and their antibacterial susceptibility in patients with chronic suppurative otitis media. Kulak Burun Bogaz Ihtis Derg; 16:164-8.

Macfadyen CA, Acuin JM, Gamble C. (2006) Systemic antibiotics versus topical treatments for chronically discharging ears with underlying eardrum perforations. Cochrane Database Syst Rev; (1):CD005608.

Indudharan R, Haq JA, Alyar S. (1999) Antibiotics in chronic suppurative otitis media: a bacteriologic study. Ann otol rhinol laryngol. 108(5):440-5.

How to cite this article:

Sandhu D, Gupta V, Chhina DK and Munjal M. Clinico-microbiological profile of Chronic Suppurative Otitis media in a Tertiary Care Hospital. Int. J. Res. Dev. Pharm. L. Sci. 2018; 7(3): 2995-2998. doi: 10.13040/IJRDPL.2278-0238.7(3).2995-2998

This Journal is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.



How to Cite

Sandhu, D. ., Gupta, V. ., Chhina, D. K., & Munjal, M. . (2018). Clinico-microbiological profile of Chronic Suppurative Otitis media in a Tertiary Care Hospital. International Journal of Research and Development in Pharmacy & Life Sciences, 7(3), 2995 - 2998.

Most read articles by the same author(s)